Priority 4 from the Living With and Beyond Cancer PSP

UNCERTAINTY: What causes fatigue in people living with and beyond cancer and what are the best ways to manage it? (JLA PSP Priority 4)
Overall ranking	4
JLA question ID	0073/4
Explanatory note	Not available for this PSP
Evidence	Causes of fatigue - some known. Spathis A, Fife K, Blackhall F, Dutton S, Bahadori R, Wharton R, O'Brien M, Stone P, Benepal T, Bates N, Wee B. Modafinil for the treatment of fatigue in lung cancer: results of a placebo -controlled, double-blind, randomized trial. Journal of Clinical Oncology 2014;32(18):1882-1888
Health Research Classification System category	Cancer

Extra information provided by this PSP
Original uncertainty examples	Why do some people become extremely fatigued, even after their disease is in remission, and what can be done to really improve how they feel? ~ What is the best way to get through the fatigue? ~ Many new treatments have evolved yet I am still very tired all the time. If treatment is available to relieve this why is it not offered? ~ How do I cope with Cancer Related Fatigue when exercise is given as a help method but it is limited because of other problems, example, I now find that due to osteoporosis exercise is difficult and not advised.
Submitted by	Individual survey submissions categorised by Healthcare professional, Patient, Relative/Carer, Other, and Unknown. For full details of the type of submitter for each individual question, please see the spreadsheet of data held on the JLA website.

Extra information provided by this PSP

Original uncertainty examples

Why do some people become extremely fatigued, even after their disease is in remission, and what can be done to really improve how they feel? ~ What is the best way to get through the fatigue? ~ Many new treatments have evolved yet I am still very tired all the time. If treatment is available to relieve this why is it not offered? ~ How do I cope with Cancer Related Fatigue when exercise is given as a help method but it is limited because of other problems, example, I now find that due to osteoporosis exercise is difficult and not advised.

Submitted by

Individual survey submissions categorised by Healthcare professional, Patient, Relative/Carer, Other, and Unknown. For full details of the type of submitter for each individual question, please see the spreadsheet of data held on the JLA website.

PSP information
PSP unique ID	0073
PSP name	Living With and Beyond Cancer
Total number of uncertainties identified by this PSP.	54 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website)
Date of priority setting workshop	11 June 2018