Priority 19 from the Anaesthesia (Canada) PSP
| UNCERTAINTY: What is the relationship between anesthetic drugs and post-operative cognitive dysfunction and memory loss in patients? (JLA PSP Priority 19) | |
|---|---|
| Overall ranking | 19 |
| JLA question ID | 0084/19 |
| Explanatory note |
This question asks about how anesthesia medications affect brain function and memory. Respondents wanted to know about the impacts of anesthesia for brain function of people of all ages. |
| Evidence |
Miller D, Lewis SR, Pritchard MW, Schofield-Robinson OJ, Shelton CL, Alderson P, Smith AF. Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non-cardiac surgery. Cochrane Database Syst Rev. 2018 Aug 21;8. https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD012317.pub2/full |
| Health Research Classification System category | Generic health relevance |
| Extra information provided by this PSP | |
|---|---|
| Original uncertainty examples | Is an elderly patient at increased risk of developing dementia due to the use of general anesthetic? ~ What is the relationship between our anesthetic drugs and postoperative cognitive dysfunction and memory loss in all ages of pts.? |
| Submitted by | Healthcare providers, caregivers, patients |
| PSP information | |
|---|---|
| PSP unique ID | 0084 |
| PSP name | Anesthesia (Canada) |
| Total number of uncertainties identified by this PSP. | 49 (To see a full list of all uncertainties identified, please see the detailed spreadsheet held on the JLA website) |
| Date of priority setting workshop | 15 May 2019 |